The researchers plan to confirm the results by analysing blood samples from lung cancer patients. Other tests identified which RNAs are packaged into extracellular vesicles and preferentially secreted from cancerous cells affected by mutant KRAS. Computer simulations identified prevalent RNA compared to control cells.Īdditional epigenomic profiling looked at how genes are turned on or off without changes to the DNA sequence itself. They performed RNA sequencing using several different methods. In Petri dishes the researchers introduced mutant KRAS into healthy lung cells, pushing them into a cancerous state. Some tumours shed DNA into the blood a long time before a person would start experiencing symptoms.Īround 360,000 people are diagnosed with cancer in the UK every year – equivalent to nearly 1,000 cases a day. This could be done through a minimally invasive technique called ‘liquid biopsy’ rather than traditional tumour tissue surgery. Lab experiments found cancer triggering variants wrongly activate others – that can be detected in the blood through sequencing, or mapping.ĭr Kim believes it is a very promising tool for for diagnosing cancer in its earliest stages. It works by looking for chemical changes in fragments of genetic code that leak from tumours into the bloodstream.
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"Relief Next to Me" thumps like wet newspaper though, her weak similes never building up to a satisfying payoff: a big chorus, a cute melody. "Knife Going In"'s instruments drift out of tune, which gives it a seasick, disconnected quality. Sara, who has the more strident voice of the two, writes their more complex songs. "Hop a Plane" does better for Tegan, because the line she repeats here is catchy enough to stay pleasurable over each iteration. Her lyrical indugences can also be difficult to swallow. Tegan's songs are conventional, so they rely on embellishment- like the Phil Collins-esque drums on "Are You Ten Years Ago"- to make them more interesting. I can only imagine that co-producer Chris Walla (Death Cab for Cutie) contributed to the problem. There's an earnestness they'd do well to drop- if they know love's a sham, and know the sham's a sham, then sing about that already- but they don't. It sounds like a rush of emotion, but flows awkwardly. Maybe they should have called it "No Exit". Lyrically, there are as many turds as gems though, and they usually appear within five words of the word "heart." "I want to draw you a floorplan of my head and heart/ I want to give directions, helpful hints, what you’ll be looking for," Sara pleads on "Floorplan". Such examples are everywhere on The Con: "When I jerk away from holding hands with you/ I know these habits hurt important parts of you," they sing on "Back in Your Head", a song that boasts the album's best keyboard lines. "Walking with a Ghost", a song later covered by the White Stripes, was perhaps its finest, if only because it showed how Tegan and Sara can add depth to heartache through keen observation. Vivek Shraya – I Take All the Blame (Bonus Track)ġ8.The duo's 2004 album So Jealous had great moments, too. Cyndi Lauper – Back in Your Head (Bonus Track)ġ7. Trashique (GRIMES X HANA) – Dark Come Soonġ5. Hayley Williams of Paramore – Nineteenġ3. The CD and digital/streaming album will be released on October 20.ġ0. The preorder for The Con X: Covers will begin on September 19 via. We are beyond grateful for the contributions of each artist, and we hope fans of The Con will be moved by their interpretations. Somehow all these new covers manage to come together to add a new chapter to The Con. It’s a universal language that bonds people together from different worlds, countries, and experiences. Music allows us to project our own stories, losses, and anxieties onto the melodies and words of someone else. All the artists agreed to donate their time and energy to the project and their labels all agreed to waive their fees as well.Īt the core of our planning was the hope that this new project would tell another chapter in the story that was The Con. Their inspiration could come from the original record or The Con Demos, our first home recordings that were released after The Con came out. We encouraged each artist to approach the song they were covering in any fashion they saw fit. With that intention set, we asked 14 artists who were either outspoken allies of the LGTBQ community or LGBTQ themselves to each cover a song from The Con. But we also wanted a companion piece that would live on past the anniversary, hence The Con X: Covers album was born.įrom day one we wanted the proceeds to go to our newly-launched Tegan and Sara Foundation, which raises money for self-identified women and girls in the LGBTQ community. Indisputably our most raw and intimate record, we wanted to ensure we created a new package that did justice to the layers of attachment that both we and our fans have had to The Con.Īlmost immediately we established that a tour playing all 14 songs in a more intimate and stripped-down arrangement would be special and memorable for our diehard fans. Important because it was the biggest leap we had made in attempting to write a cohesive group of songs that told a painful and anxious story about our different relationships to loss, death, love, compulsion, fear, letting go and moving on. Important not just because of the music or the elaborate way we approached recording it 10 years ago with Chris Walla. This past winter, as the 10th anniversary of The Con quickly approached, Sara and I started to brainstorm meaningful ways to celebrate what was easily one of our most important records. The new version also requires the active participation of players, which usually makes it more fun. This is a big advantage that the participants of the game overlooked. Not only does this allow for smooth gameplay, it allows players to install AI on their mobile devices. The new version of the game runs on a standalone app. Since then, the developer has completely improved and greatly improved the Axie Infinity. As a result, we found it very difficult to learn the game. However, the developer did not publish almost any information about the game strategy. That’s why we haven’t criticized X-Infinity on this issue. However, most blockchain games at the time were browser-based and did not require active gaming. Instead, players simply had to send their axes into battle with repetitive movements in advance. And active participation of the player in the gameplay is not required. And we saw it as a plus.Īxis Infinity, on the other hand, was a simple browser game with limited graphics. We call this the “ultimate fantasy tricks” approach to the monster breeding style. When we faced Axis Infinity about a year ago, the combat system got more complicated than the other blockchain games we tried. This guide will walk you through setting up your digital wallet, purchasing Axis, and downloading apps. Download the application form from the download field on this pageĪxis Infinity is a digital pet universe where players select, select and trade fantasy items called Axis.Log in here with a metamask and set your email/password.Larvae and petite require additional treatments to grow before they can be used in combat. Download a digital wallet like MetMask and load it with some ETH.How to install and get started XE Infinity for real money.You can download Xi Infinity Android from the link we share in the download section on our site. Players can create a collection of axes and use them in the expanding universe of the game!Īxis uses the latest technology called blockchain to reward the commitment of endless players. What is Axie Infinity?Īxis are monstrous creatures that love to fight, build and find treasure! I left my axis thinking I would never play like that again. I have to wait a few hours for my axis to fight again. (In fact, I lost my password and bought a new truck in 2019.) 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Address: 1909 Bellamah Avenue Northwest, Albuquerque, New Mexico 87104. For additional details about the merchants, special events, and more, visit the market’s website or Facebook page. News from Dezeen Events Guide, a listings guide covering the leading design-related events taking place around the world. Located in Albuquerques historic Sawmill District, Sawmill Market is an artisanal food hall that celebrates culinary traditions and emerging trends alike. and you pay just for the food, drinks, or artisan goods you purchase. News about our Dezeen Awards programme, including entry deadlines and announcements. Dezeen Jobsĭaily updates on the latest design and architecture vacancies advertised on Dezeen Jobs. Dezeen DailyĪ daily newsletter containing the latest stories from Dezeen. Plus occasional updates on Dezeen’s services and breaking news. Sent every Tuesday and containing a selection of the most important news highlights. Plus occasional updates on Dezeen’s services and breaking news. Sawmill market is a really beautifully put together food hall with a lot of variety, eye and stomach candy, seating (indoor and outdoor) with local vendors who were all incredibly friendly and passionate about their offerings. Sent every Thursday and featuring a selection of the best reader comments and most talked-about stories. Our most popular newsletter, formerly known as Dezeen Weekly. Other food hall designs are Malmö Market Hall in a former freight depot in Sweden, a food court in Mexico City by MYT+GLVDK and a street-food market in the Netherlands in an old grain silo. 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"Most materials were sourced within a 10-mile radius." "We utilised adaptive reuse and creative salvage everywhere we could," said the studio. Related story Islyn Studio creates soothing atmosphere in Brooklyn’s Bond Vet clinic But taking the activist angle, it can also be a song about the meaning of life and trying to discover what one's grand purpose in life truly is. On the surface it could very well be a love song. It's no secret that Goldfinger frontman John Feldmann is an outspoken activist, a staunch vegetarian and political rabble rouser (we mean that in a good way, mind you), so with that knowledge in mind, the song takes on several meanings. "Superman" - Goldfinger (culled from Hang Ups, 1997) The Man of Steel goes ska! While the music on this tune screams "Party!/Good Times!" the lyrics are an interesting mix of potentially socio-political introspection. 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Cause I can't be your Superman/Can't be your Superman/Can't be your Superman/Can't be your Superman/I can't be your Superman/Can't be your Superman/Can't be your Superman/Your Superman, your Superman. 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